Defiance Real Estate Search

Defiance 5 Bedroom Properties for Sale

Our website features the best real estate search for 5 bedroom properties available in Defiance and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official REALTOR®’s database every 15 minutes. 

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Newest Defiance 5 Bedroom Properties for Sale

1177 August Lake Dr, Defiance
$1,685,000
5 Beds ⋅ 7 Baths ⋅ 26065331 MLS ⋅ ACTIVE UNDER CONTRACT Status
Set on an exceptional three-acre homesite, this distinguished residence blends timeless elegance, refined craftsmanship, and modern luxury. Hardwood floors extend throughout the home, creating a warm and cohesive foundation for its beautifully appointed interiors. At the heart of the home is a stunning, fully renovated kitchen completed in 2024, thoughtfully designed with custom inset cabinetry, exquisite marble countertops and backsplash, an integrated marble shelf, a 48-inch professional range, a statement 55-inch hood, and an expansive 72-inch refrigerator. Unlacquered brass Cremone bolts, faucets, and cabinet hardware add a sophisticated designer touch, while a built-in coffee machine and renovated butler’s pantry with abundant storage and a dedicated coffee bar elevate everyday living and entertaining. Offering five bedrooms, five full bathrooms, and two half baths, the home provides exceptional space for both intimate living and grand-scale entertaining. A convenient main-level laundry room adds everyday functionality, while the attached eight-car garage offers an extraordinary amount of space for vehicles, storage, and recreational pursuits. Significant updates provide added peace of mind, including a new roof in 2025, HVAC updates in 2024 and 2025, and a new water heater in 2025. The backyard was fully fenced in 2022 and complemented by extensive landscaping, creating a private outdoor retreat across the expansive grounds. Additional improvements include a renovated powder room and hardwood flooring in the basement in 2022, fresh interior paint throughout in 2022, new exterior doors, and exterior painting in 2023. An unfinished basement with a private entrance presents exceptional potential for future customization, whether envisioned as private guest or multigenerational living quarters, a dedicated home office, fitness studio, or additional recreational space. A rare opportunity to enjoy space, sophistication, and versatility on three picturesque acres, with thoughtfully curated finishes, substantial recent improvements, and endless possibilities to tailor the home to your lifestyle.

1177 August Lake Dr, Defiance
2275 Hwy F, Defiance
$7,250,000
5 Beds ⋅ 4 Baths ⋅ 26057899 MLS ⋅ ACTIVE UNDER CONTRACT Status
Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son Nathan and nephew/adopted son Jonathan Bryan helped shape this remarkable landscape. A captivating driveway leads around to a ONE-OF-A-KIND property built in the 1840’s for Jonathan Bryan. “Bryan Mill” rests gracefully on 105.4+/- acres providing a peaceful & tranquil atmosphere, conveniently located near Augusta & Defiance, with a STRIKING, FINELY DETAILED, FULLY FURNISHED, FRENCH INSPIRED w/exquisite imported antiques curated by Annie Brahler of EuroTrash, Inc. At the heart of the property is an 1840s built cottage exquisitely reimagined as a luxurious country residence, and STATELY early 1800’s built 68’x36’ Stone mill/outbuilding with 2 BEAUTIFUL automatic solid wood doors, floor-to-ceiling Stone fireplace, 37’+/- vaulted ceiling, kitchen, 2 half baths, & an abundant amount of storage space, AND a COMPLETELY REDONE stone chicken coop. Throughout the cottage, historic details have been carefully preserved and complemented by modern mechanical systems, conveniences, and automated security and surveillance. The home boasts 2,815+/- SqFt, 5 bedrooms, 2 full baths, with mostly original hardwood flooring throughout and a kitchen anchored by a 65 inch La Cornue Chateau Series range. The historic mill is equally remarkable. Beautifully restored and fully climate-controlled with modern HVAC systems, the mill features a catering kitchen and expansive event and entertaining spaces. It offers an extraordinary setting for private dinners, celebrations, retreats, creative pursuits, or large-scale entertaining—all without ever leaving the privacy of the estate. Create a legacy where your children and grandchildren can reconnect with nature—plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. Beyond the residence, private acreage unfold through rolling fields, mature woods, gardens, and majestic private pathways winding throughout the estate. A dramatic boulder firepit creates an intimate destination for evenings outdoors, while even the custom chicken coop has been thoughtfully designed to complement the architecture and character of the property. Opportunities to own a tract with this combination of history, natural beauty, privacy, and location are exceptionally rare, especially with frontage on the coveted Hwy F. This isn't just land—it's a place where your family's next chapter can begin and memories can be made for generations to come. MUST SEE! Today, you have the rare opportunity to own 105.4+/- acres of beautiful land just off Highway F, conveniently located near Augusta and Defiance, with over $1,000,000 of road and infrastructure improvements completed creating multiple opportunities for building sites on the property with electric, well and septic in place. With breathtaking ridge-top views and rolling countryside, this property is the perfect setting for a private family retreat, a picturesque mini ranch, or private equestrian estate. Create a legacy where your children and grandchildren can reconnect with nature—plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. *ALL PARTIES UNDERSTAND PROPERTY IS SUBJECT TO SURVEY AND APPROVED THROUGH CITY & ALL GOVERNMENTAL AUTHORITIES.* Seller will also consider dividing the property in different ways. Acreage sold SEPARATELY. See MLS #’s: 26053202 (LOT #1, 22+/- ACRES), 26053203 (LOT #2, 12.5+/- ACRES), 26053360 (LOT #3, 38.5+/- ACRES), & 26053204 (LOT #4, 32+/- ACRES).

2275 Hwy F, Defiance
2275 Hwy F, Unit LOT 1, Defiance
$3,450,000
5 Beds ⋅ 4 Baths ⋅ 26053202 MLS ⋅ ACTIVE UNDER CONTRACT Status
Imagine owning a timeless piece of Missouri history. More than 250 years ago, the Osage people traveled these valleys, and pioneers like Daniel Boone, his son Nathan and nephew/adopted son Jonathan Bryan helped shape this remarkable landscape. A captivating driveway leads around to a ONE-OF-A-KIND property built in the 1840’s for Jonathan Bryan. “Bryan Mill” rests gracefully on 22+/- acres providing a peaceful & tranquil atmosphere, conveniently located near Augusta & Defiance, with a STRIKING, FINELY DETAILED, FULLY FURNISHED, FRENCH INSPIRED w/exquisite imported antiques curated by Annie Brahler of EuroTrash, Inc. At the heart of the property is an 1840s built cottage exquisitely reimagined as a luxurious country residence, and STATELY early 1800’s built 68’x36’ Stone mill/outbuilding with 2 BEAUTIFUL automatic solid wood doors, floor-to-ceiling Stone fireplace, 37’+/- vaulted ceiling, kitchen, 2 half baths, & an abundant amount of storage space, AND a COMPLETELY REDONE stone chicken coop. Throughout the cottage, historic details have been carefully preserved and complemented by modern mechanical systems, conveniences, and automated security and surveillance. The home boasts 2,815+/- SqFt, 5 bedrooms, 2 full baths, with mostly original hardwood flooring throughout and a kitchen anchored by a 65 inch La Cornue Chateau Series range. The historic mill is equally remarkable. Beautifully restored and fully climate-controlled with modern HVAC systems, the mill features a catering kitchen and expansive event and entertaining spaces. It offers an extraordinary setting for private dinners, celebrations, retreats, creative pursuits, or large-scale entertaining—all without ever leaving the privacy of the estate. Create a legacy where your children and grandchildren can reconnect with nature—plant gardens, raise animals, ride horses, explore miles of side-by-side trails, or simply enjoy the peace and beauty that only a property like this can offer. Beyond the residence, private acreage unfold through rolling fields, mature woods, gardens, and majestic private pathways winding throughout the estate. A dramatic boulder firepit creates an intimate destination for evenings outdoors, while even the custom chicken coop has been thoughtfully designed to complement the architecture and character of the property. Opportunities to own a tract with this combination of history, natural beauty, privacy, and location are exceptionally rare, especially with frontage on the coveted Hwy F. This isn't just land—it's a place where your family's next chapter can begin and memories can be made for generations to come. MUST SEE! *ALL PARTIES UNDERSTAND PROPERTY IS SUBJECT TO SURVEY AND APPROVED THROUGH CITY & ALL GOVERNMENTAL AUTHORITIES.* Additional acreage FOR SALE. See MLS #’s: 26053203 (LOT #2, 12.5+/- ACRES), 26053360 (LOT #3, 38.5+/- ACRES), & 26053204 (LOT #4, 32+/- ACRES).

2275 Hwy F, Unit LOT 1, Defiance
220 Northlind Dr, Defiance
$1,400,000
5 Beds ⋅ 7 Baths ⋅ 26037028 MLS ⋅ ACTIVE Status
Stunning brick and stone ranch-style home sitting on 3 private acres surrounded by mature trees and scenic views! This custom-built home boasts 5 bedrooms, 4 full bathrooms, 3 half bathrooms, and over 6,500 square feet of living space including the finished walkout lower level. The property also features an attached 3 car garage and a detached 52 x 40 foot detached garage with a bonus room. The front door opens to the impressive entry foyer with a gallery staircase and leads to the elegant dining room and stunning great room. The great room boasts a floor-to-ceiling brick fireplace, custom millwork, a wall of windows overlooking the grounds, and French doors that open to the expansive deck. The designer kitchen features custom glazed cabinetry, granite countertops, commercial-grade appliances, a butler’s pantry, dining area with a bay window, and opens to the hearth room with a beautiful brick and stone fireplace. The light-filled sunroom provides the perfect place to relax and enjoy the picturesque setting. The luxurious main floor primary suite boasts a brick fireplace, private sitting area, deck access, walk-in closets, and a spa-like bathroom with a jetted tub, separate shower, and dual vanities. The stylish powder room and laundry room complete the main level. The finished walkout lower level is designed for entertaining and features a spacious recreation room with a stone fireplace, wet bar, office, workout room, guest suite, two additional bedrooms connected by a Jack and Jill bathroom, and a half bathroom. The lower level also features ample storage space. Other highlights include: extensive custom millwork, coffered ceilings, professional landscaping, multiple waterfalls, newer hardwood floors on the main level, and painted neutral colors throughout most of the home. Relax outside on the expansive deck overlooking the scenic grounds, enjoy the beautifully landscaped yard with waterfalls. Location could not be better – close to major highways, restaurants, shops, parks, hiking trails, wineries, and Francis Howell schools!

220 Northlind Dr, Defiance
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Listings courtesy of Mid America Regional Information Systems Internet Data Exchange as distributed by MLS GRID.


Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker of MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. Some listings have been excluded from this website.


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